Specificity of digoxin immunoassays toward digoxin metabolites
نویسندگان
چکیده
منابع مشابه
Renal disease and digoxin immunoassays.
Daunorubicin (Cerubidin) No No No No Dacarbazine (DTIC) Yes No No No Vindesine (Eldisine) Yes No No No 5-Fluorouracil (Fluoro-uracil) No No No No Mithramycin (Mithracin) No No No No Mitomvcin (mitomycin C, Kyowa) No No No No Mustine hydrochloride (Mustine) Yes No No No CyclophosphaITiide (Endoxan-Asta) No No No No Doxorubicin (Adriamycin) Yes No Yes Yes Cytarabine (Cytosar-U) No No No No Actino...
متن کاملEffect of antibody specificity on results of selected digoxin immunoassays among various clinical groups.
We examined the specificity of three automated digoxin immunoassays (Abbott TDxFLx Digoxin II assay, Baxter-Dade Stratus II Digoxin assay, and Ciba Corning ACS Digoxin assay) applied without modification to (a) sera from 229 digoxin-free patients in 12 cohorts associated with nonspecific or endogenous digoxin-like immunoreactive factor (DLIF) interference, and (b) drug-free serum supplemented w...
متن کاملMethods for eliminating interferences in digoxin immunoassays caused by digoxin-like factors.
Endogenous, circulating digoxin-like immunoreactive factors (DLIF) are known to cross react with many antisera used in digoxin assays, complicating the quantification of serum digoxin. We have explored ways to decrease or remove the interference from DLIF in such assays. Prolonging the assay incubation from 30 to 60 min decreased apparent digoxin concentrations (attributable to DLIF) by an aver...
متن کاملDigoxin immunoassay with cross-reactivity of digoxin metabolites proportional to their biological activity.
Our objective was to identify commercially available digoxin immunoassays whose cross-reactivity with digoxin metabolites paralleled the pharmacological activity of the metabolites. We measured the immunoreactivity of digoxigenin bis- and monodigitoxosides, digoxigenin, and dihydrodigoxin in four immunoassays and compared the immunoactivities with pharmacological activities from studies involvi...
متن کاملComparable effects of DIGIBIND and DigiFab in thirteen digoxin immunoassays.
tients. Clin Chem 1995;41:256–63. 9. Niederwieser G, Bonelli RM, Brunner D, Neubauer M, Buchinger W, Reisecker F, et al. Diagnostic accuracy of an agarose gel electrophoretic method in multiple sclerosis. Clin Chem 2001;47:144. 10. Cavuoti D, Baskin L, Jialal I. Detection of oligoclonal bands in cerebrospinal fluid by immunofixation electrophoresis. Am J Clin Pathol 1998;109:585–8. 11. Richard ...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1994
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/40.7.1348